Allele frequency of hyperkalemic periodic paralysis (HYPP) in quarter horses from Mexico
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چکیده
منابع مشابه
Hyperkalemic Periodic Paralysis Synonym: HyperPP
Hyperkalemic periodic paralysis (hyperPP) is characterized by attacks of flaccid limb weakness (which may also include weakness of the muscles of the eyes, throat, and trunk), hyperkalemia (serum potassium concentration >5 mmol/L) or an increase of serum potassium concentration of at least 1.5 mmol/L during an attack of weakness and/or provoking/worsening of an attack by oral potassium intake, ...
متن کاملA case of hyperkalemic periodic paralysis.
た.し か し発熱,筋 ・関節痛はな く,知 覚異常も 自覚 しなかつた.筋 脱力は四肢に限局し,頭 頚部 およ び躯幹の異常はなかつた.発 病後約1週 間徐 徐に増悪 したのち快方に向い,約1ヵ 月間の通院 治療で全治した.そ の後は特別の症状なく普通に 生活 していたがが,昭 和43年(15才 時)8月 初旬, 野球大会に投手 として出場のための練習で過労がが 続いたのち,同 月12日,最 終試合を 終えて 帰宅 後,夕 食前,午 後6時 頃から両手の脱力を覚え, 翌13日 朝は両下肢 の脱力が加わ り,さ らに夕刻に は軽度の嚥下障害も認められ,14日 には腰腹筋脱 力,15日 には起坐 ・歩行全 く不能 とな り,8月17 日当科に入院 した. 入院時現症:意 識清明.起 坐 ・歩行全 く不能 で受動的背臥位であるが,心 ・肺お よび腹部内臓 には異常なく,軽 度の嚥下障害を...
متن کاملHyperkalemic periodic paralysis M1592V mutation modifies activation in human skeletal muscle Na1 channel
CECILIA V. ROJAS,1 ALAN NEELY,2 GABRIELA VELASCO-LOYDEN,1 VERÓNICA PALMA,3 AND MANUEL KUKULJAN3 1Instituto de Nutrición y Tecnologı́a de los Alimentos, Universidad de Chile, Casilla 138-11, Santiago; and 3Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Casilla 70005-7, Santiago, Chile; and 2Department of Physiology, Texas Tech University Health Sciences Center, Lubb...
متن کامل[Hyperkalemic periodic paralysis: a Spanish family with the p.Thr704Met mutation in the SCN4A gene].
INTRODUCTION Hyperkalemic periodic paralysis (HYPP) is an autosomal dominant disease characterized by recurrent episodes of muscular weakness with increased blood potassium levels. Here we present the clinical, analytical, neurophysiological and genetic findings of family with eight affected individuals, five of which were available for study. PATIENTS AND METHODS The five patients were subje...
متن کاملA sodium channel defect in hyperkalemic periodic paralysis: potassium-induced failure of inactivation.
Hyperkalemic periodic analysis (HPP) is an autosomal dominant disorder characterized by episodic weakness lasting minutes to days in association with a mild elevation in serum K+. In vitro measurements of whole-cell currents in HPP muscle have demonstrated a persistent, tetrodotoxin-sensitive Na+ current, and we have recently shown by linkage analysis that the Na+ channel alpha subunit gene may...
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ژورنال
عنوان ژورنال: African Journal of Biotechnology
سال: 2014
ISSN: 1684-5315
DOI: 10.5897/ajb2013.13176